Prometheus may refer to:
- The Prometheus Combat Support Bridgelayer.
- The Prometheus, the Clan-tech FrankenMech that served as the testbed for the Direct Neural Interface system.
- "Prometheus", the name of the custom configured Daishi belonging to Victor Steiner-Davion.
- Operation Prometheus, the Rim Worlds Republic/Lyran Commonwealth espionage campaign that resulted in the theft of BattleMech technology from the Terran Hegemony.
- The Prometheus database, a massive library created by the Terran Hegemony; the Helm Memory Core and Hegemony Memory Core comprise only a fraction of the contents of this lost database.
- The Potemkin-class cruiser Prometheus
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