Knights-Grasse Syndrome
Knights-Grasse Syndrome was a degenerative disease which caused intense pain, but generally was not fatal for many years.[1] The syndrome was first identified in the late twenty-first century, and people were still known to die from it as of 2367.[2]
Those impacted by this syndrome included Captain-General Mikhail Marik, whose autopsy confirmed he was in the intermediate stages of the disease at the time of his death.[1][2]